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. 2022 Nov 15;7(6):e00471-22. doi: 10.1128/msphere.00471-22

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Copyright © 2022 Jackson et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 3 — Heatmap displaying positive predictive value (PPV) of the presence of antibiotic resistance genes and phenotypic nonsusceptibility to antimicrobial agents used in the treatment of UTI. The PPV of each genotype-phenotype classification was calculated and visually displayed in the form of a heatmap. A PPV of 0 is shown in white, whereas a PPV of 1 is dark pink. Ninety-five percent confidence intervals were calculated by bootstrapping. Hierarchical clustering was applied to the genes included in this analysis. The heatmap was created with the heatmap package using R 3.0.1. Amp/Sul, ampicillin-sulbactam; Pip/Taz, piperacillin-tazobactam; TMP/SMZ, trimethoprim-sulfamethoxazole.