FIG 4.

Dysbiosis of the oropharyngeal microbiota in hospitalized patients (COVID and non-COVID) compared to local controls. (A) Discriminative bacterial genera distinguishing hospitalized patients from local controls by LEfSe. Difference in the relative abundance tested by pairwise Mann-Whitney U test and Tukey’s HSD post hoc test are shown on the right panels. (B) Hierarchical cluster analyses using distance matrix of discriminative bacterial genera classified the surveyed samples into two clades based on the dendrogram topologies, with a heat map indicating the relative abundance.