FIG 2.

Combination of the fractal globule model and the equilibrium globule model of genome organization in rust fungi. (A) Contact maps showing frequencies of pairwise 3D genome contacts. Colors represent number of contacts inferred from Hi-C data. Centromeres are highlighted by arrowheads. (B) Reconstructed 3D genomes based on the beads-on-a-string model. Each bead is 500 bp, and each colored string represents one chromosome. (C) Centromere and telomere locations in the reconstructed 3D genomes. Centromeres and telomeres are represented by golden and lemon spheres, respectively. (D) Log-log plot of intra- and interchromosome contact probability P(s) as a function of genomic distance. The dashed lines are linear fitting slopes of the P(s) curves. CYR34 and 93-210 are isolates of Puccinia striiformis f. sp. tritici (the wheat stripe rust pathogen) and Pgt21-0 is an isolate of P. graminis f. sp. tritici (the wheat stem rust pathogen).