Disease status classification using SCAD-related gut microbes and serum metabolites. (A), (C), and (E) Cumulative AUC of model by recursive feature elimination based on SCAD-related microbial species, serum metabolites and their combination, respectively. Dash line indicated the best features selected for final model. (B), (D), and (F) ROC of the 5-fold cross-validated random forest classifiers composed of the selected microbial species, serum metabolites, and their combination, respectively.