TABLE 1.
Ferret antisera against human seasonal vaccine strains or candidate virus vaccines (CVVs) demonstrated variable recognition of the swine H1 1A.1.x lineagea
| Strain | Category | Clade | A/Ohio/24/2017 | IDCDC-RG59 a/Ohio/24/2017-like | A/Ohio/9/2015 RG48A | A/Idaho/7/2018 |
|---|---|---|---|---|---|---|
| IDCDC-RG59 A/Ohio/24/2017-like | CVV | 1A.1.1 | 5120 | 2560 | <10 | 1,280 |
| A/swine/Iowa/A02478635/2019 | Test | 1A.1.1 | 160 | 160 | 10 | 80 |
| A/swine/Oklahoma/A02245237/2019 | Test | 1A.2 | 40 | 20 | 320 | 2,560 |
| A/swine/Texas/A01104132/2019 | Test | 1A.2-3-like | 20 | 20 | 80 | 1,280 |
| A/Ohio/9/2015 | CVV | 1A.3.3.3 | <10 | <10 | 1,280 | 10 |
| A/swine/North Carolina/A02478571/2019 | Test | 1A.3.3.3 | <10 | 10 | 1,280 | 20 |
| A/swine/Iowa/A01731653/2016 | Test | 1A.3.3.3 | 10 | <10 | 160 | 20 |
| A/swine/Nebraska/A02214231/2017 | Test | 1A.3.3.3 | 10 | <10 | 320 | 10 |
| A/Idaho/7/2018 | Human vaccine | 1A.3.3.2 | 80 | 160 | 160 | 10,240 |
| A/swine/Utah/A02432386/2019 | Test | 1A.3.3.2 | 80 | 40 | 160 | 5,120 |
a
Hemagglutination inhibition (HI) titers of CVV or human seasonal vaccine antisera against the contemporary North American swine H1 1A.1.x lineage. Homologous titers are highlighted in gray, and boxes mark titers against swine viruses of the same lineage.