TABLE 2.
Comparison of MIC values for aztreonam/avibactam and aztreonam alone as determined concurrently by broth microdilution and agar dilution susceptibility testing against Enterobacterales
| Aztreonam/avibactam | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Fold-difference—broth MIC vs. agar MIC |
||||||||||
| Organism | Na | EAb | ≥–8 | –4 | –2 | 0 | +2 | +4 | ≥+4 | ≥+8 |
| Enterobacterales | 201 | 97.0% | 26 | 97 | 72 | 4 | 2 | |||
| E. coli | 57 | 96.5% | 12 | 23 | 20 | 1 | 1 | |||
| K. pneumoniae | 48 | 97.9% | 4 | 26 | 17 | 1 | ||||
| Proteus spp. | 20 | 100.0% | 2 | 10 | 8 | |||||
| E. cloacae | 29 | 93.1% | 2 | 12 | 13 | 2 | ||||
| Citrobacter spp. | 18 | 100.0% | 2 | 12 | 4 | |||||
| Other | 29 | 96.6% | 4 | 14 | 10 | 1 | ||||
Number of evaluable isolates (isolates for which the fold-difference as indicated could be determined based on the MIC).
EA, essential agreement (MIC value identical or within 2-fold between methods; shaded in gray).