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. 2022 Nov 7;10(6):e03601-22. doi: 10.1128/spectrum.03601-22

TABLE 2.

Comparison of MIC values for aztreonam/avibactam and aztreonam alone as determined concurrently by broth microdilution and agar dilution susceptibility testing against Enterobacterales

Aztreonam/avibactam
Fold-difference—broth MIC vs. agar MIC
Organism Na EAb ≥–8 –4 –2 0 +2 +4 ≥+4 ≥+8
Enterobacterales 201 97.0% 26 97 72 4 2
E. coli 57 96.5% 12 23 20 1 1
K. pneumoniae 48 97.9% 4 26 17 1
Proteus spp. 20 100.0% 2 10 8
E. cloacae 29 93.1% 2 12 13 2
Citrobacter spp. 18 100.0% 2 12 4
Other 29 96.6% 4 14 10 1
a

Number of evaluable isolates (isolates for which the fold-difference as indicated could be determined based on the MIC).

b

EA, essential agreement (MIC value identical or within 2-fold between methods; shaded in gray).