TABLE 3.

Contributions of genes to penicillin resistance and biofilm formation and potential transcriptional regulation in S. aureus ATCC 43300 in response to GE-EE

Gene	Contribution toa:		Regulation associated with indicated global regulatory gene (% of positively regulated contributors)b
	Penicillin resistance	Biofilm formation	agr (25)	sarA (83)	sigB (92)	luxS
atlA	−	+		N	P
blaZ	+		N	P
cidA	−	+		N	P
clfA		+	N	P	P
clfB		+	N	P	P
coa		+	N	P	P
crtN		+	P	P	P
ebpS		+	N	P	P
fnbA		+	N	P	P
icaA		+		P	P	N
hla		+	P	P	N
hld		−	P	P	N
lrgA	+	−	P	P	N
mecA	+	+	P	P	P
psmα		−	P	P	N
sspA		−	P	N	N
vwb		+	N	P	P

^a−, negative contributor; +, positive contributor.

^bThe values in parentheses are the percentages of positively regulated contributors to biofilm formation associated with each regulatory gene. N, negative regulation; P, positive regulation.