TABLE 2.

Insect bioassays were performed to determine lethal concentration and lethal time for 50% mortality of target hosts

Insect stage	Fungal strain	Time (days)	Mean value ± SE (range) for:
			LC50 (conidia/mL)	LT50 (days)
Adult	WT	5	6.22 × 107 ± 8.33 × 107 (4.53 × 106, 8.56 × 108)	5.91 ± 0.46 (5.07, 6.89)
		10	2.24 × 105 ± 1.18 × 105 (7.96 × 104, 6.32 × 105)
	ΔFPPS1	5	5.85 × 105 ± 2.60 × 105 (2.45 × 105, 1.40 × 106)	3.27 ± 0.21 (2.88, 3.71)
		10	2.25 × 104 ± 0.94 × 104 (0.99 × 104, 5.10 × 104)
	ΔFPPS1::FPPS1	5	3.35 × 107 ± 3.6 × 107 (4.05 × 106, 2.76 × 108)	5.66 ± 0.43 (4.87, 6.58)
		10	2.74 × 105 ± 1.39 × 105 (1.01 × 105, 7.43 × 105)
	Const-FPPS1a	5	2.09 × 108 ± 3.32 × 108 (9.25 × 106, 4.71 × 109)	6.69 ± 0.61 (5.59, 8.0)
		10	6.12 × 105 ± 3.60 × 105 (1.93 × 105, 1.94 × 106)
	MaUV-HV	5	3.28 × 106 ± 3.28 × 106 (4.63 × 105, 2.32 × 107)	4.5 ± 0.30 (3.94, 5.13)
		10	3.56 × 104 ± 1.67 × 104 (1.42 × 104, 8.95 × 104)
4th instar	WT	5	2.17 × 107 ± 2.09 × 107 (3.27 × 106, 1.43 × 108)	6.22 ± 0.54 (5.25, 7.36)
		10	6.55 × 105 ± 4.24 × 105 (1.85 × 105, 2.33 × 106)
	ΔFPPS1	5	8.19 × 105 ± 4.80 × 105 (2.59 × 105, 2.58 × 106)	3.7 ± 0.24 (3.26, 4.20)
		10	4.16 × 104 ± 1.88 × 104 (1.71 × 104, 1.01 × 105)
	Const-FPPS1	5	2.78 × 107 ± 2.42 × 107 (5.10 × 106, 1.52 × 108)	7.18 ± 0.76 (5.83, 8.84)
		10	2.00 × 106 ± 1.53 × 106 (4.48 × 105, 8.93 × 106)
	MaUV-HV	5	4.03 × 106 ± 3.54 × 106 (7.24 × 105, 2.25 × 107)	4.95 ± 0.32 (4.35, 5.59)
		10	7.58 × 104 ± 3.38 × 104 (3.15 × 104, 1.82 × 105)

^aThe const-FPPS1 strain is the MaFPPS1 constitutive expression strain (MaFPPS1^Const in the text).