TABLE 4.
Growth responses of primary strains of Gram-negative respiratory bacteria to fluticasone proprionatea
| Organism | % growth change | P |
|---|---|---|
| Achromobacter spp. | 19.0 | 0.004 |
| Acinetobacter baumannii | 347.6 | <0.001 |
| Citrobacter koseri | 7.9 | 0.45 |
| Enterobacter spp. | –2.0 | 0.013 |
| Escherichia/Shigella | 27.2 | 0.019 |
| Klebsiella spp. | 30.5 | <0.001 |
| Klebsiella aerogenes | 12.9 | 0.001 |
| Klebsiella grimontii | 16.2 | 0.002 |
| Klebsiella oxytoca | 1.9 | 0.68 |
| Klebsiella variicola | 13.8 | <0.001 |
| Pseudomonas spp. (not P. aeruginosa) | –2.5 | 0.065 |
| Pseudomonas aeruginosa | 47.7 | <0.001 |
| Serratia marcescens | 47.8 | <0.001 |
| Stenotrophomonas maltophilia | 38.8 | <0.001 |
Experiments were repeated up to four times, and differences in growth were averaged over the experiments. Values were measured at the time of maximal response for each species. The statistical difference between vehicle and fluticasone conditions was determined using a Student t test.