TABLE 2.
Distribution of NOS MICs among M. tuberculosis isolatesa
| Classification | No. (%) of strains with MIC (μg/mL) |
MIC50 | MIC90 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.016 | 0.031 | 0.062 | 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | >8 | Total | |||
| Non-MDR | 0 | 2 | 6 | 12 | 5 | 12 | 5 | 0 | 1 | 1 | 0 | 44 | 0.125 | 1 |
| MDR | 2 | 8 | 12 | 26 | 18 | 10 | 5 | 1 | 1 | 0 | 1 | 84 | 0.125 | 0.5 |
| Simple MDR-TB | 0 | 5 | 9 | 14 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 35 | 0.125 | 0.25 |
| MDR-TB plus | 2 | 3 | 3 | 12 | 13 | 10 | 4 | 1 | 1 | 0 | 0 | 49 | 0.25 | 1 |
| Total | 2 | 10 | 18 | 38 | 23 | 22 | 10 | 1 | 2 | 1 | 1 | 128 | 0.125 | 1 |
a
MIC50, concentration required to inhibit the growth of 50% of the isolates tested. MIC90, concentration required to inhibit the growth of 90% of the isolates tested; Simple MDR-TB, MDR-TB with susceptible to fluoroquinolone or three second-line injectable drugs (capreomycin, kanamycin, and amikacin); MDR-TB plus, MDR-TB with additional resistance to any fluoroquinolone and to at least one of three second-line injectable drugs.