TABLE 3.
Hotgen result by onset of symptoms and vaccinated individuals in Brazil and the UKc
| Cohort | BR, university center |
BR, community center |
UK, drive-through |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ag-RDT positive (n, %) | Ag-RDT negative (n, %) | Sensitivitya | 95% CI | Ag-RDT positive (n, %) | Ag-RDT negative (n, %) | Sensitivitya | 95% CI | Ag-RDT positive (n, %) | Ag-RDT negative (n, %) | Sensitivitya | 95% CI | |
| Days from symptom onset | ||||||||||||
| Days <0–3 | 28, 16.5% | 142, 83.5% | 93.3% | 76.5, 98.8 | 21, 33.3% | 42, 66.7% | 95.% | 75.1, 99.8 | 48, 24.2% | 150, 75.7% | 87.3% | 75.5, 94.7 |
| Days 4–7 | 26, 19.4% | 108, 80.6% | 92.9% | 75, 98.9 | 17, 27.9% | 44, 72.1% | 77.3% | 54.2, 91.3 | 8, 25.0% | 24, 75.0% | 100% | 63.1, 100.0 |
| Days 8+ | 1, 20.0% | 4, 80.0% | 50.0% | 2.7, 97.3 | 2, 16.7% | 10, 83.3% | 66.7% | 12.5, 98.2 | 0, 0.0% | 13, 100.0% | NA | NA |
| Vaccination received | ||||||||||||
| Vaccinated | 18, 14.3% | 108, 85.7% | 85.7% | 62.6, 96.2 | 6, 21.4% | 22, 78.6% | 75.0% | 35.9, 95.5 | 16, 13.2% | 105, 86.8% | 69.6% | 47.1, 86.8 |
| Incomplete vaccinationb | 22, 21.6% | 80, 78.4% | 100% | 85.1, 100 | 1, 50% | 1, 50% | 100% | 20.7, 100 | 22, 30.1% | 51, 69.9% | 95.6% | 78.1, 99.9 |
| Not vaccinated | 15, 18.5% | 66, 81.5% | 88.2% | 65.7, 96.7 | 33, 30.82% | 74, 69.2% | 86.8% | 72.7, 94.2 | 18, 34.6% | 33, 63.4% | 90% | 68.3, 98.7 |
| Not disclosed | NA | NA | NA | NA | NA | NA | NA | NA | 1, 100.0% | 0, 0.0% | 100.0% | 2.5, 100.0 |
a
Compared to RT-qPCR.
b
Single dose received.
c
CI, confidence interval; Ag-RDT, antigen-based rapid diagnostic test; BR, Brazil; NA, not available.