TABLE 2.
Protective efficacy of intramuscular Z11ΔrfbG vaccination
| Vaccination |
No. | Challenge |
No. of survivors/no. total | Survival rate (%) | ||||
|---|---|---|---|---|---|---|---|---|
| Strain | Route | Dose (CFU) | Strain | Route | Dose (CFU) | |||
| Z11ΔrfbG | Intramuscularly | 5 × 105 | 15 | Z11 | Intramuscularly | 7 × 108 | 13/15 | 86.7 |
| 5 × 106 | 15/15 | 100 | ||||||
| 5 × 107 | 15/15 | 100 | ||||||
| PBS | 11/15 | 73.3 | ||||||
| PBS | 15/15 | 100 | ||||||