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. 2022 Nov 29;10(6):e03344-22. doi: 10.1128/spectrum.03344-22

TABLE 2.

Sensitivity and specificity of the cascade detection system and PCR for detecting mcr-1, blaNDM, tet(X4)/tet(X6), and blaKPCa

XDR gene No. of results
Sensitivity, % Specificity, %
PCR (+), cascade system (+) PCR (+), cascade system (−) PCR (−), cascade system (+) PCR (−), cascade system (−)
mcr-1 25 1 1 68 96.2 (25/25 + 1) 98.6 (68/68 + 1)
bla NDM 19 1 1 74 95.0 (19/19 + 1) 98.7 (74/74 + 1)
tet(X4)/tet(X6) 23 2 1 69 92.0 (23/23 + 2) 98.6 (69/69 + 1)
bla KPC 21 1 2 71 95.5 (21/21 + 1) 97.3 (71/71 + 2)

aSensitivity, positive samples detected by both PCR and cascade system/total positive samples; specificity, negative samples detected by both PCR and cascade system/total negative samples.