TABLE 2.
Protective efficacy of Md5BAC ΔmeqΔpp38 in SPF chickens
| Vaccinationa | Challengeb | Tumors (%)c | Lesions (%)d | PIe |
|---|---|---|---|---|
| CVI988/Rispens | Md5BAC | 1/13 (7.7) | 1/13 (7.7) | 88.2 |
| Md5BAC ΔmeqΔpp38 | Md5BAC | 0/13 (0) | 0/13 (0) | 100 |
| None | Md5BAC | 4/20 (20) | 13/20 (65) | N/Af |
| None | None | 0/12 (0) | 0/12 (0) | N/Af |
Chickens were vaccinated with 2,000 PFU of the indicated viruses.
Chickens were challenged with 500 PFU Md5BAC at day 5 post-vaccination. “None” means no virus inoculation.
Tumors (%) = incidence of Marek’s disease specific gross tumors.
Incidence of Marek’s disease-specific gross lesions.
PI = protective index.
N/A = not applicable.