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. 2022 Nov 9;10(6):e02871-22. doi: 10.1128/spectrum.02871-22

TABLE 2.

Protective efficacy of Md5BAC ΔmeqΔpp38 in SPF chickens

Vaccinationa Challengeb Tumors (%)c Lesions (%)d PIe
CVI988/Rispens Md5BAC 1/13 (7.7) 1/13 (7.7) 88.2
Md5BAC ΔmeqΔpp38 Md5BAC 0/13 (0) 0/13 (0) 100
None Md5BAC 4/20 (20) 13/20 (65) N/Af
None None 0/12 (0) 0/12 (0) N/Af
a

Chickens were vaccinated with 2,000 PFU of the indicated viruses.

b

Chickens were challenged with 500 PFU Md5BAC at day 5 post-vaccination. “None” means no virus inoculation.

c

Tumors (%) = incidence of Marek’s disease specific gross tumors.

d

Incidence of Marek’s disease-specific gross lesions.

e

PI = protective index.

f

N/A = not applicable.