TABLE 2.

Proteins with largest changes in abundance after growth in minimal medium plus 0.2 mM Pi compared to minimal medium plus 1 mM Pi

Locus tag	Gene	Protein name	Protein function/comment	Log2 FC	Ref.
Depleted
PA0196	pntB	Pyridine nucleotide transhydrogenase, beta subunit	Regulation of NAD(P)+/NAD(P)H redox homeostasis	−7.27	111
PA1680		Predicted 3-oxoadipate enol-lactonase activity	Predicted role in benzoate catabolism	−6.46	112
PA1555	ccoP2	Cytochrome c oxidase, cbb3-type, CcoP subunit	Respiratory electron transfer chain component	−6.36
PA2840		ATP-dependent RNA helicase	Regulation of type 3 secretion system	−6.30	113
PA1297	aitP	Metal transporter	Fe2+ and Co2+ export	−6.18	114
PA3321		Transcriptional regulator		−6.10
PA0141		Polyphosphate kinase	GTP synthesis	−6.06	115
PA5118	thiI	Thiazole biosynthesis protein	Thiazole synthesis	−6.02
PA1964		ATP-binding component of ABC transporter	Transport	−5.98
PA4243	secY	Secretion protein SecY	Protein export	−5.93
Enriched
PA3330		Probable short-chain dehydrogenase	Regulated by quorum sensing	8.62	116
PA4214a  PA1903a	phzE1 phzE2	Phenazine biosynthesis protein PhzE Phenazine biosynthesis protein PhzE	Phenazine (pyocyanin) biosynthesis, host interaction Phenazine (pyocyanin) biosynthesis, host interaction	7.90 7.90	117
PA4216a  PA1905a	phzG1 phzG2	Probable pyrridoxamine 5′-phosphate oxidase Probable pyrridoxamine 59-phosphate oxidase		7.33 7.33
PA3280	oprO	Pyrophosphate-specific outer membrane porin OprO	Phosphate and diphosphate transport	6.45	51
PA3279	oprP	Phosphate-specific outer membrane porin OprP		6.36
PA5360	phoB	Two-component response regulator PhoB	Transcriptional regulation in response to Pi starvation	6.33	118
PA4211	phzB1	Phenazine biosynthesis protein	Phenazine biosynthesis	6.13	117
PA0690	pdtA	Phosphate depletion regulated two-partner secretion system partner A	Secretion system involved in virulence	5.97	119
PA0696		Hypothetical protein	Unknown, part of the σVreI regulon, upregulated by Pi	5.92	120, 121
PA0698		Hypothetical protein		5.80

^aProteins of the same sequence.