TABLE 1.
Composition of the vaginal microbiome in vaginitisa
| Condition | Vaginal microbiome features |
|---|---|
| Cytolytic vaginosis | Overgrowth of Lactobacillus spp. (20) |
| Bacterial vaginosis | Enrichment of Atopobium vaginae,b BVAB1, BVAB2, BVAB3, Gardnerella vaginalis, Mobiluncus spp., Mycoplasma spp., Porphyromonas spp., Prevotella spp., Sneathia spp., and Ureaplasma spp. (44); depletion of Lactobacillus spp. (44) |
| Vulvovaginal candidiasis | Normal to BV-like vaginal microbiome (19, 120, 122); colonization by Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis, or Candida krusei (19, 120, 122) |
| Trichomoniasis | BV-like vaginal microbiome (133, 134); invasion by Trichomonas vaginalis (133, 134) |
| Aerobic vaginitis or desquamative inflammatory vaginitis | Depletion of Lactobacillus spp. (29, 139); frequent detection of aerobic, enteric bacteria, e.g., E. coli, Enterococcus spp., Staphylococcus spp., and Streptococcus spp. (29, 139) |
a
BVAB1, “Candidatus Lachnocurva vaginae”; BVAB2, Lachnospiraceae BV-associated bacterium 2; BVAB3, Mageeibacillus indolicus.
b
A. vaginae was reclassified to a new genus and renamed Fannyhessea vaginae in 2018 (266).