FIG 7.

Global phylogeny of M. avium subsp. paratuberculosis. A maximum likelihood SNP-based phylogenetic tree of all type C genomes included in this study was inferred using IQ-Tree (TVM+F model). PICSAR77 was used as the reference, and homoplasic sites were removed. The tree was midpoint rooted. The scale of the tree is by site substitution. Previously described phylogenetic clades are shown as leaves on the tree. The outer circle was colored according to continent of origin of isolates. The blue-shaded section indicates the monophyletic group carrying the mutation in the gyrB gene.