TABLE 1.
Microbiological and genomic characteristics of the ST65 strains
| Itema | P1 | PEKP4222 | P6 | PEKP4130 | B3 | PEKP3083 | PEKP3048 | PEKP123 | A7 | J4 |
|---|---|---|---|---|---|---|---|---|---|---|
| HMV | Y | Y | Y | Y | Y | Y | Y | N | Y | Y |
| MDR | Y | Y | N | N | N | N | N | N | N | N |
| CR | Y | N | N | N | N | N | N | N | N | N |
| Biofilm | + | + | + | + | + | + | + | ++ | + | + |
| Serum killing assay | Sensitive | Sensitive | Sensitive | Resistant | Resistant | Sensitive | Resistant | Sensitive | Sensitive | Resistant |
| AMR | blaOXA-1; blaCTX-M-3; blaKPC-3 | tetA | N | N | N | N | N | N | N | N |
| Serotype | KL2 | KL2 | KL2 | KL2 | KL2 | KL2 | KL2 | KL2 | KL2 | KL2 |
| O-antigen | O1v2 | O1v2 | O1v2 | O1v2 | O1v2 | O1v2 | O1v2 | O1v2 | O1v2 | O1v2 |
| yersiniabactin | Ybt17-ICEKP10 | Ybt17-ICEKP10 | N | Ybt17-ICEKP10 | Ybt17-ICEKP10 | N | Ybt17-ICEKP10 | Ybt17-ICEKP10 | Ybt17-ICEKP10 | N |
| Colibactin | clb3 | clb3 | N | clb3 | clb3 | N | clb3 | clb3 | clb3 | N |
| Aerobactin | iuc1 | iuc1 | iuc1 | iuc1 | iuc1 | iuc1 | iuc1 | iuc1 | iuc1 | N |
| Salmochelin | iro1 | iro1 | iro1 | iro1 | iro1 | iro1 | iro1 | iro1 | iro1 | iro1 |
| RmST | 38 | 38 | 38 | 38 | 38 | 38-1LV | 38 | 38 | 38 | 38 |
| Virulence scoreb | 5 | 5 | 3 | 5 | 5 | 3 | 5 | 5 | 5 | 3 |
HMV, hypermucoviscosity; MDR, multidrug resistance; CR, carbapenem resistance; AMR, antimicrobial resistance; Y, yes; N, no.
Virulence score was predicted using Kleborate. Bold texts represent the characteristics of the two MDR-ST65-hvKp strains.