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Survival of gene knockout mice challenged with a high dose of E. cuniculi spores. Five- to six-week-old female CD4−/−, CD8−/−, and wild-type (WT) C57BL/6 mice were infected i.p. with 5 × 107 spores of E. cuniculi. Animals were monitored on a daily basis. The study was performed twice with similar results.
