Fig 2. Estimated benefit from a hypothetical screening blood test with typical versus best-available treatment.

This figure illustrates expert ratings on the estimated benefit from a hypothetical screening test, defined as the improvement in curability as a result of the test on a scale of 1 (not at all likely to increase) to 9 (increase a great deal), when considering typical versus best available treatment. Typical treatment was defined as the care provided to the population as a whole; best available treatment was defined as guideline-concordant care. Items in grey represent no difference in ratings for typical versus best available treatment. Items in blue represent a difference in ratings for typical versus best available treatment, with the dark blue representing typical treatment and light blue representing best available treatment.