TABLE 2.
Distribution of clinical H. pylori strains among the different hybridization patterns
| Pattern typea | Clinical strains (n = 43)
|
Strains from patients with gastritis (n = 26)
|
Strains from patients with cancer (n = 17)
|
P | |||
|---|---|---|---|---|---|---|---|
| No. | % | No. | % | No. | % | ||
| Cluster A | 13 | 30.2 | 8 | 30.8 | 5 | 29.4 | 0.92 |
| Branch A1 | 6 | 13.9 | 4 | 15.4 | 2 | 11.8 | 0.9 |
| Branch A2 | 7 | 16.3 | 4 | 15.4 | 3 | 17.6 | 0.8 |
| Cluster B | 30 | 69.8 | 18 | 69.2 | 12 | 70.6 | 0.92 |
| Branch B1 | 21 | 48.8 | 11 | 42.3 | 10 | 58.8 | 0.3 |
| Branch B2 | 9 | 20.9 | 7 | 26.9 | 2 | 11.7 | 0.4 |
a
The patterns were classed using a dendrogram. Cluster A includes strains which contain less than seven plasticity region ORFs and is subdivided into two branches, A1, which contains the ORFs located in the center of the plasticity region (from JHP937 to JHP942), and A2, which includes strains with one ORF or none. Cluster B includes strains carrying seven or more selected ORFs and is subdivided into two branches, B1, in which these ORFs are dispersed throughout the genome, and B2, where the ORFs are located in the central part of the plasticity region (see also Fig. 3).