FIG. 3.

Effects of H. pylori products on IL-2 production by PBMCs and Jurkat T cells. PBMCs and Jurkat T cells were incubated with various concentrations of different H. pylori products with PHA plus PMA for 24 h as in Fig. 2. In the absence of PHA plus PMA, IL-2 secretion by resting cells was below the detection limit (0.1 U/ml). Values and number of experiments are as in Fig. 2. # and ##, significant increase (#, P < 0.05; ##, P < 0.01). ∗ and ∗∗, significant decrease (∗, P < 0.05; ∗∗, P < 0.01). The top row of symbols refers to urease values, the middle row refers to lysate, and the bottom row refers to intact bacteria.