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Effect of H. pylori DNA on cytokine secretion by PBMCs. PBMCs were cultured with H. pylori DNA alone or with PHA plus PMA (mitogen-activated PBMCs). IFN-γ (A), IL-12p40 (B), and IL-2 (C) were assayed in duplicate by ELISA. Values are means ± standard errors of three experiments (same three donors as in Fig. 1). Dunnett's test was used for statistical analysis. ∗, P < 0.05 versus none.
