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. 2022 Dec 21;8(51):eadd2337. doi: 10.1126/sciadv.add2337

Fig. 1. Intercellular labeling system for studying CCIs with molecular resolution.

Fig. 1.

Schematic diagram of the FucoID system for detecting, isolating, and analyzing a broad spectrum of CCIs. The FucoID system contains two probes, cell-sFT (probe 1) and Ab-sFT (probe 2), built on the sFT conjugates. As a specific, versatile, and quantitative proximity labeling system, FucoID enables the quantification of the strength and the discovery of molecular signatures of CCIs through the multiple analyzing methods after labeling and isolation, e.g., flow cytometry and RNA-seq analyses.