FIG. 3.

Survival after L. donovani infection in untreated (A) and AmB-treated mice (B). (A) Results are from two experiments in which a total of 18 WT controls (squares) and 20 TNF KO mice (circles) were infected but were not given antileishmanial treatment. (B) Results are from a single experiment in which infected TNF KO mice were (i) left untreated (open circles; n = 12 mice), (ii) given three AmB injections during weeks 2 to 3 only (hatched circles; n = 8), or (iii) treated similarly with AmB during weeks 2 to 3 and then given once-weekly AmB during weeks 4 to 7 (filled circles; n = 8).