TABLE 4.
Mediation analyses: effects of social deprivation on preemptive kidney transplantation (one mediator at a time)
| Living-donor transplantation | Positive CMV serology | HLA immunization | Positive hepatitis C serology | Blood group B | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
| Natural direct effect | 0.69 | [0.61-0.78]** | 0.65 | [0.57-0.75]** | 0.64 | [0.56-0.73]** | 0.64 | [0.55-0.73]** | 0.64 | [0.56-0.73]** |
| Natural indirect effect | 0.92 | [0.89-0.95]** | 0.98 | [0.95-1.00]* | 1.00 | [0.99-1.00] | 0.99 | [0.99-1.00]* | 0.99 | [0.98-1.00]* |
| Total effect | 0.64 | [0.56-0.73]** | 0.63 | [0.56-0.73]** | 0.63 | [0.55-0.73]** | 0.63 | [0.55-0.73]** | 0.63 | [0.55-0.73]** |
The analyses were adjusted for confounders: age, sex, diabetes, and underlying nephropathy.
*P < 0.05.
**P < 0.001.
CI, confidence interval; CMV, cytomegalovirus; OR, odds ratio.