Table 1. Comparison of lidocaine versus EMLA cream following LP.
EMLA cream | Lidocaine | p -Value | |
---|---|---|---|
LP and local analgesia characteristics | |||
Initial randomized local analgesic | 5 (50%) | 5 (50%) | |
Adverse local reaction to analgesic | 0 (0%) | 0 (0%) | |
Minutes between local analgesic and start of LP, median (min–max) | 145 (85–213) | 2 (1–6) | |
Amount of lidocaine, mL, median (min–max) | – | 2 (1.5–3.0) | |
Number of lidocaine sticks, median (min–max) | – | 1 (1–3) | |
LP needle sticks, median (min–max) | 1 (1–3) | 1 (1–5) | |
Required more 1 LP needle stick | 2 (20%) | 2 (20%) | |
Resident involvement in lumber puncture | 2 (20%) | 3 (30%) | 1.00 |
Signs of pain with local analgesia Increase in heart rate Movement |
0 (0%) | 5 (50%) 1 4 |
0.03 |
Wong-Baker Faces Pain Rating Scale Scores | |||
Baseline, pre-LP
Any reported pain (WBS > 0) Pre-LP, median (min–max) |
0 (0%) 0 (0–0) |
0 (0%) 0 (0–0) |
|
30–60 minutes post-LP
Any reported pain (WBS > 0) 30–60 minutes post-LP, median (min–max) |
0 (0%) 0 (0–0) |
0 (0%) 0 (0–0) |
|
24 hours post-LP
Any reported pain (WBS > 0) 24 hours post-LP, median (min–max) |
2 (20%) 0 (0–8) |
3 (30%) 0 (0–8) |
1.00 0.79 |
PRN pain medication 24 hours post-LP | |||
Acetaminophen
Any reported pain, n (%) mg, median (min–max) |
1 (10%) 0 (0–325) |
2 (20%) 0 (0–1290) |
1.00 0.18 |
Opioid
Any reported pain, n (%) mg, median (min–max) |
0 (0%) 0 (0–0) |
1 (10%) 0 (0–5.325) |
1.00 0.32 |
Abbreviations: LP, lumbar puncture; PRN, pro re nata; WBS, Wong-Baker FACES Pain Rating Scale.