Table 3.
The mortalities in patients with different acid-base disorders.
| Total | AG< 8 mmol/L | 8 ≤ AG ≤ 16 mmol/L | AG> 16 mmol/L | P † | |
|---|---|---|---|---|---|
| Normal∗ | |||||
| Subjects, n (%) | 1167 | 1 (0.1) | 590 (50.6) | 576 (49.4) | |
| ICU mortality, n (%) | 114 (9.8) | 1 (100.0) | 34 (5.8) | 79 (13.7) | <0.001 |
| Hospital mortality, n (%) | 187 (16.0) | 1 (100.0) | 60 (10.2) | 126 (21.9) | <0.001 |
| Acid-base disorder with a normal blood pH# | |||||
| Subjects, n (%) | 2432 | 11 (0.5) | 1007 (41.4) | 1414 (58.1) | |
| ICU mortality, n (%) | 276 (11.3) | 0 (0) | 77 (7.6) | 199 (14.1) | <0.001 |
| Hospital mortality, n (%) | 468 (19.2) | 1 (9.1) | 133 (13.2) | 334 (23.6) | <0.001 |
| Blood pH < 7.35 | |||||
| Subjects, n (%) | 3785 | 27 (0.7) | 1186 (31.3) | 2572 (68.0) | |
| ICU mortality, n (%) | 698 (18.4) | 6 (22.2) | 115 (9.7) | 577 (22.4) | <0.001 |
| Hospital mortality, n (%) | 952 (25.2) | 6 (22.2) | 155 (13.1) | 791 (30.8) | <0.001 |
| Blood pH>7.45 | |||||
| Subjects, n (%) | 1136 | 3 (0.3) | 455 (40.1) | 678 (59.7) | |
| ICU mortality, n (%) | 134 (11.8) | 0 (0) | 35 (7.7) | 99 (14.6) | 0.001 |
| Hospital mortality, n (%) | 202 (17.8) | 0 (0) | 58 (12.7) | 144 (21.2) | 0.001 |
∗ Patients with 7.35 ≤ blood pH ≤ 7.45, 22 ≤ HCO3− ≤ 26 mmol/L, and 35 ≤ PaCO2 ≤ 45 mmHg; # patients with 7.35 ≤ blood pH ≤ 7.45 and abnormal HCO3− or PaCO2; †P values indicated the differences of mortalities between groups with serum AG > 16 mmol/L and 8 ≤ AG ≤ 16 mmol/L. AG, anion gap; ICU, intensive care unit.