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The major mechanisms of tumor resistance. (A) Biological barriers[48]. Reproduced with permission from ref[48]. Copyright 2020 American Chemical Society. (B) Drug inactivation[40]. Reproduced with permission from ref[40]. Copyright 2021 American Chemical Society. (C) DNA damage repair[61]. Reproduced with permission from ref[61]. Copyright 2022 the authors. (D) Immune evasion[69]. Reproduced with permission from ref[69]. Copyright 2020 Science.
