Table 2.
Overview of fetal and preterm lambs at delivery and necropsy.
| Experimental groups | |||
|---|---|---|---|
| Fetal control | Preterm SAL | Preterm LPS | |
| Gestational age at delivery (days) | 136.6 ± 1.0 | 129.7 ± 1.4 | 128.9 ± 1.0 |
| Postconceptional age at necropsy (days) | 136.6 ± 1.0 | 137.9 ± 1.9 | 135.4 ± 1.3 |
| N (male) | 7 (4) | 9 (4) | 9 (4) |
| Body weight at delivery (kg) | 4.05 ± 0.45 | 2.90 ± 0.41* | 3.22 ± 0.37* |
| Body weight at necropsy (kg) | 4.05 ± 0.45 | 2.79 ± 0.39* | 2.97 ± 0.24* |
| Heart weight (g) | 29.4 ± 3.7 | 23.7 ± 3.1* | 24.8 ± 3.8 |
| Heart weight: body weight at necropsy (g/kg) | 7.32 ± 1.18 | 8.64 ± 1.61 | 8.36 ± 1.05 |
| LV wall thickness (mm) | 6.6 ± 0.8 | 7.3 ± 0.6 | 7.5 ± 0.8 |
| IVS wall thickness (mm) | 7.6 ± 0.9 | 6.1 ± 0.9* | 6.2 ± 0.6* |
| RV wall thickness (mm) | 5.0 ± 0.5 | 3.8 ± 0.4* | 4.5 ± 0.4† |
Statistical analyses were performed using a one-way ANOVA followed by a Bonferroni post hoc test. Data are presented as mean ± SD. Significance accepted at p < 0.05: *significant difference compared to fetal control, †significant difference compared to preterm SAL.