Table 4.
Survival of male schistosomes post treatment and their reproduction potential.
| Group | No. mice | Survival rate of male schistosomes post treatment |
Production potential of male schistosomes post treatment (No. miracidia per worm pair) |
||
|---|---|---|---|---|---|
| Mean, SD | Median, Range | Mean, SD | Median, Range | ||
| Control | 12 | 0.62, 0.17 | 0.65, 0.24–0.84 | 138.42, 97.49 | 119.39, 16.53–340.81 |
| PZQ 200 mg/Kg | 12 | 0.45, 0.31 | 0.45, 0.02–0.93 | 243.05, 284.42 | 100.64, 17.02–1020.07 |
| PZQ 400 mg/Kg* | 13 | 0.06, 0.15 | 0.00, 0.00–0.49 | 80.75, 121.40 | 8.075, 13.56–262.69 |
| Kruskal-Wallis Test | Chi-squared = 21.23, df = 2, P < 0.0001 | Chi-squared = 3.41, df = 2, P = 0.1814 | |||
Note: *, Multiple comparisons showed significant difference only between PZQ 400 mg/kg and either Control (K-W test, Chi-squared = 17.45, df = 1, P < 0.0001) or PZQ 200 mg/kg (Chi-squared = 13.13, df = 1, P = 0.0003) in terms of survival rate of male schistosomes post treatment.