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. 2022 Oct 18;74(12):2024–2031. doi: 10.1002/art.42283

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© 2022 The Authors. Arthritis & Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Overall immune cell composition in JDM compared to cSLE skin was predominantly innate immune cells. A and B, Bar graphs showing percent composition of immune cell types by disease (A) and innate versus adaptive immune cell categorization, with CD14+ and CD68+ macrophages, pDCs, and mDCs categorized as innate, and CD4+ and CD8+ T cells and B cells as adaptive (B). * = P < 0.05 versus JDM. C, Innate versus adaptive immune cell enrichment from skin microarrays of the same patients. Bars show the mean ± SD. D, Bar graph showing individual patient sample immune cell composition. IMC = imaging mass cytometry (see Figure 1 for other definitions).