Skip to main content
. 2022 Oct 18;74(12):2024–2031. doi: 10.1002/art.42283

Figure 3.

Figure 3

Cell–cell interactions in JDM and cSLE lesional skin using neighborhood analysis. A and B, Heatmaps highlighting differences in cell–cell interactions in JDM (A) and cSLE (B) lesional skin using permutation tests for neighborhood analysis. Red represents a positive association (P < 0.01), white represents an insignificant association, and blue represents a negative association (P < 0.01). C, Multiplexed images demonstrating staining for cellular markers in JDM and cSLE skin samples, represented by different colors in panels 1–5. Bars = 100 μm. D, Demonstration of increased epithelial cell–immune cell interaction in cSLE compared to JDM lesional skin, and an overall more prominent endothelial cell–immune cell interaction in JDM. Magnification is the same as in C. See Figure 1 for definitions.