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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Am Geriatr Soc. 2022 Aug 5;70(12):3538–3548. doi: 10.1111/jgs.17976

Table 2:

Disease specific, General QOL Measures and Functional Capacity

Questionnaire Overall (N=47) Amyloid Absent (N=31) Amyloid Present (N=16)
TTR (N=10) Indeterminant (N=6)
n Mean ± SD Median (Q1 - Q3) n Mean ± SD Median (Q1 - Q3) n Mean ± SD Median (Q1 - Q3) n Mean ± SD Median (Q1 - Q3)
Swiss Spinal Stenosis Questionnaire
 Symptom severity (range 1 to 5) 27 2.7±0.9 2.7 (2.1, 3.2) 14 2.9±1.1 2.8 (2.3, 3.8) 9 2.5±0.7 2.7 (2.1, 3) 4 2.6±0.8 2.5 (2.1, 3.1)
 Functional disability (range 1 to 4) 27 2.2±0.7 2.2 (1.6, 2.7) 14 2.3±0.9 2.6 (1.5, 3) 9 2±0.7 2 (1.6,2.2) 4 2.4±0.2 2.4 (2.4, 2.5)
Oswestry Low Back Pain Questionnaire
 Total percent score (range 0 to 100) 24 38±19.6 41 (23.5, 53) 15 41.5±18.8 42 (25.5, 54.5) 6 22.8±18.1 24 (12.8, 26.3) 3 51±9.6 47 (45.5, 54.5)
KCCQ scores (range 0 to 100)
 Physical limitation 24 71.4±26.2 77.1 (54.2, 91.7) 12 74.3±27.9 83.3 (65.7, 93.8) 8 68.8±27.1 77.1 (40.7, 91.7) 4 67.7±24.6 64.6 (54.2, 78.1)
 Symptom stability 26 51.9±9.6 50 (50, 50) 14 53.3±12.9 50 (50, 50) 8 50±0 50 (50, 50) 4 50±0 50 (50, 50)
 Symptom frequency 27 83.3±24.8 92.7 (79.2, 100) 14 83.2±27.9 95.8 (85.4, 100) 9 84.3±25.5 100 (87.5, 100) 4 81.3±13.3 78.2 (75, 84.4)
 Symptom burden 27 83.6±20 91.7 (75, 100) 14 83.9±23 91.7 (83.3, 100) 9 82.4±18.8 91.7 (75, 100) 4 85.4±12.5 83.4 (75, 93.8)
 Total symptom 27 83.5±21.7 89.6 (81.3, 100) 14 83.6±24.8 91.7 (82.3, 99) 9 83.4±21.5 89.6 (81.3, 100) 4 83.4±12.5 80.8 (75.1, 89.1)
 Self-efficacy 27 83±25.7 100 (75, 100) 14 89.2±20 100 (87.5, 100) 9 76.4±33.3 87.5 (75, 100) 4 75±27 81.3 (65.6, 90.6)
 Quality of life 24 88.3±16.7 91.7 (83.3, 100) 14 91.1±12.4 100 (87.5, 100) 7 78.6±24 91.7 (62.5, 95.9) 3 97.2±4.8 100 (95.9, 100)
 Social limitation 15 75.3±33.1 93.8 (59.4, 100) 8 70.8±39 100 (37.5, 100) 4 79.7±32.8 93.8 (73.5, 100) 3 82.7±16.7 81.3 (74, 90.7)
 Clinical summary 27 78.8±22 87.5 (70.8, 94.1) 14 80.3±24.5 87.5 (81.1, 94.3) 9 77.8±21.2 87.5 (67.8, 90.7) 4 75.6±17.4 71.7 (68.3, 78.9)
 Overall summary 24 82.1±18 88.9 (74.5, 95.3) 14 82.9±17.7 88.9 (77.9, 93.5) 7 79.8±21.7 82.3 (75.5, 94.5) 3 83.5±15.6 81.3 (75.2, 90.7)
SF-36 (range 0 to 100)
 Physical functioning 27 46.7±24.2 50 (27.5, 60) 14 42.5±21.6 42.5 (26.3, 60) 9 53.9±31.3 50 (25, 70) 4 45±14.7 45 (33.8, 56.3)
 Role limitations due to physical health 27 34.3±42.3 0 (0, 75) 14 42.9±40.9 37.5 (0, 75) 9 36.1±48.6 0 (0, 100) 4 0±0 0 (0, 0)
 Role limitations due to emotional problems 27 59.3±46.5 100 (0, 100) 14 59.5±45.6 83.3 (8.3, 100) 9 74.1±43.4 100 (66.7, 100) 4 25±50 0 (0, 25)
 Energy/fatigue 27 55±18.4 60 (42.5, 65) 14 57.9±18.1 60 (46.3, 72.5) 9 53.3±20.8 55 (45, 60) 4 48.8±16.5 50 (37.5, 61.3)
 Emotional well-being 27 76.7±15.6 84 (68, 88) 14 77.4±15.3 84 (68, 87) 9 76.4±16.2 80 (76, 84) 4 75±20 80 (66, 89)
 Social functioning 27 70.8±32.9 75 (56.3, 100) 14 61.6±37.5 75 (31.3, 87.5) 9 94.4±11 100 (100, 100) 4 50±17.7 56.3 (43.8, 62.5)
 Pain 27 47.5±26.9 45 (27.5, 68.8) 14 40.4±28.5 37.5 (22.5, 57.5) 9 63.9±22.4 60 (57.5, 77.5) 4 35.6±13.8 32.5 (30, 38.1)
 General health 27 59.4±18.1 60 (47.5, 72.5) 14 60±18.8 57.5 (50, 73.8) 9 58.3±21.9 50 (45, 75) 4 60±4.1 60 (58.8, 61.3)
Physical function
 SPPB total score 22 8±3.4 9 (7, 10) 8 8.4±3.6 10 (8.5, 10) 9 7.3±4.2 7 (6, 11) 5 8.8±1.1 9 (9, 9)
 6MWT distance (m) 21 292±103 304 (220, 346) 8 256±93 240 (220, 290) 8 316±138 332 (166, 428) 5 311.2±7.6 310 (304, 318)