Table 1.

Anti-AM/LAM mAbs with known reactivity to glycan structural motifs

Species	mAb	Epitope(s) Recognized	Isotype	Method	Strain/Antigen	References
Human	T1AM09	Long chain Ara	IgG1	Single B cell sort	TST+ IGRA- subject sorted w/ Mtb H37Rv AM	[79]
	L1AM04	Man3	IgG1		TST+ IGRA+ subject sorted w/ Mtb H37Rv AM	[79]
	A194–01	Ara4/Ara 6 +/− Man1	IgG1	B cell culture	TB+ subject cultured w/ Mtb Erdman ManLAM	[70, 76]
	P83A8	Ara4/Ara 6	IgG1
	P30B9	Man2	IgM
	P95C1	Man only	IgM
	P65H1	Man2 cap	IgM
	My2F12	Ara4/Ara6 + Man2	IgG1	Phage display library	Non-immune screened w/ Mtb AoyamaB ManLAM	[80]
Murine	CS-35	Ara4/Ara6 +/− caps	IgG3	Hybridoma	Immunization w/ M. leprae i.p	[65, 68]
	CS-40	Ara4/Ara6 + Man1 +/− MTX	IgG3		Immunization w/ Mtb Erdman ManLAM i.p.	[71, 72]
	922.5*	Ara4/Ara6	IgG3		Immunization w/ M. leprae, boost w/ LAM i.p.	[68]
	908.1*	Ara4/Ara6	IgG3
	FIND25*	Ara6+/− cap	IgG1		Immunization w/ hk Mtb H37Rv and LAM i.p.	[69]
	FIND28*	Ara6 + Man cap	IgG1
	FIND170*	Ara6 +/− cap	IgG1
	9d8	Ara6 + Man1/Man2	IgG3		Immunization w/ hk Mtb Erdman i.p.	[53, 66]
Rabbit	27D2	Ara4/Ara6 +/− Man1	IgG	B cell culture	Immunization w/ synthetic LAM OS motifs (S#16, S#44, S#22), boosted on days 7 and 14	[76]
	13H3	Ara6 +/− Man1	IgG
	S4–20+	Man Cap + MTX	IgG1	Phage display library	Immunization w/ BCG and hk Mtb H37Ra s.c. screened w/ LAM	[77]
	O-TB×	Man Cap +/− MTX	IgG1
Chicken	G3^	Man Cap − MTX	IgG1

Epitope(s) recognized: the AM/LAM structural motifs predominantly recognized by the respective mAb. Method: describes methodology used to isolate mAb; Strain/Antigen: describes immunization and other factors contributing to mAb generation. Mtb.: Mycobacterium tuberculosis; i.p.: intra-peritoneal; s.c.: subcutaneous; hk.: heat-killed. Detailed information on reactivities to AM oligosaccharide motifs is shown in Figure 2.

^*:mAbs clonally related to some others listed, including to those in supplemental Table S1 (see online Supplemental Information Table S1).

Other names for mAbs:

⁺MoAb1,

^×MoAb3,

^{^}MoAb2