FIG. 6.

Effect of the treatment with PAF antagonist on the parasite load in lymph nodes and spleen. Mice were infected and treated with BN52021 as described in Fig. 4. At 2, 5, and 7 weeks post-infection the animals were killed and the popliteal lymph nodes (A) and spleens (B) were removed for quantification of the parasite load by limiting dilution. The data are expressed as the log₁₀ of the number of parasites/gram of tissue and are shown as the mean ± the SEM of four animals. ∗, P < 0.01 (comparing the drug-treated group with the vehicle-treated group at each time point).