TABLE 1.

Effect of PAF antagonist on the infection index^a

Treatment (M)	Mean infection index ± SEM at 48 h
None	287.53  ± 11.30
PAF (10−6)	163.24  ± 13.20*
WEB2170	419.57  ± 57.28*
PAF plus WEB2170	308.41  ± 4.80#

^aTG-elicited, C57BL/6 mouse peritoneal macrophages infected with L. (L.) amazonensis were treated with PAF at the moment of infection. WEB2170 (10⁻⁵ M) was added to macrophage cultures 1 h before the addition of PAF to infected cultures. The infection index was determined in 48-h cultures. In each group, three different macrophage suspensions were analyzed. Each suspension consisted of a pool of peritoneal cells obtained from at least two animals and was assayed in duplicate. The data represent the mean ± the SEM of six coverslips examined. ∗, P < 0.05 (compared to vehicle-treated group); #, P < 0.05 (compared to the group treated with PAF).