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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Alcohol Clin Exp Res. 2022 Nov 9;46(12):2203–2213. doi: 10.1111/acer.14965

Table 2 –

Effects of Ethanol on Gating Rate Constants

kf+ kf− ks+ ks− o+ o−
GluN2A
Control 4110 ± 207 2860 ± 379 423 ± 21.3 956 ± 126 4880 ± 407 657 ± 67.8
EtOH 3870 ± 272 2600 ± 275 303 ± 14.3*** 829 ± 88.3 5063 ± 498 984 ± 104***
GluN2B
Control 3540 ± 436 2120 ± 310 56 ± 3.1 1040 ± 98.5 3020 ± 361 379 ± 14.2
EtOH 3200 ± 495 2830 ± 870 39 ± 3.01*** 993 ± 172 2540 ± 512 497 ± 40.6*

Rate constants obtained from fitting open and shut events within bursts to a kinetic model (Fig. 5C). Values (in s−1) are the means ± S.E. from N = 7 patches. Asterisks denote significant differences from control (paired t-tests; *** P < 0.001, * P < 0.05)