Table 3.
Significant DMRs in regional analyses based on the meta-analyses on the homogeneous probes in both sex and race/ethnicity in WHI and NAS.*
| chr | Start a | End a | Sidak p-value | Number of CpGs | Covered CpGs a | Annotated Gene a | Other close gene a |
|---|---|---|---|---|---|---|---|
|
| |||||||
| 5 | 68710808 | 68711278 | 1.43×10−10 | 7 | cg02505827, cg05901765, cg06418871, cg06998965, cg12687157, cg17019292, cg18663063 | MARVELD2 | - |
| 10 | 131567747 | 131568314 | 3.07×10−05 | 6 | cg01079118, cg13742952, cg14308082, cg18583565, cg22768615, cg23889967 | - | MGMT |
| 1 | 228890801 | 228891037 | 4.34×10−05 | 5 | cg16061472, cg20462561, cg23012917, cg23926439, cg25138412 | - | RHOU |
| 19 | 51774377 | 51774667 | 1.98×10−3 | 3 | cg14724749, cg14884932, cg15497724 | - | SIGLECL1 |
Abbreviations: DMRs, differentially methylated regions; CpG, cytosine-phosphate-guanine; chr, chromosome.
*
We defined significant DMRs as one with ≥3 CpGs and Sidak p-value<0.05.
a
The University of California Santa Cruz UCSC database (GRCh37/hg19)