TABLE 2.
Amount of 28-kDa SpeB produced by GAS isolated from invasive cases of varying severity
| Isolate source (n) | Amt of 28-kda SpeB (μg/ml)a
|
Pb | |
|---|---|---|---|
| Mean ± SD | Median | ||
| Nonsevere infection (29) | 270 ± 183 | 243 | |
| Severe infection (48) | 190 ± 171 | 200 | 0.05 |
| STSS (17) | 141 ± 162 | 117 | 0.02 |
| NF (20) | 196 ± 176 | 221 | 0.16 |
| STSS + NF (11) | 257 ± 167 | 333 | 0.80 |
a
The amounts of secreted SpeB in culture supernatants were determined by Western blot analysis as described in Materials and Methods.
b
Differences between the amounts of SpeB produced by isolates from nonsevere infections and isolates from various subgroups of the severe infections were evaluated by the Student t test.