Table 1.
Echocardiography data table of systolic and ventricular filling parameters.
| CI, ml/min/g | FS, % | EDV, ml | ESV, ml | HR, beats/min | |
|---|---|---|---|---|---|
| CQ pre-treatment | 0.110 ± 0.026 | 33.625 ± 0.632 | 1.231 ± 0.072 | 0.404 ± 0.031 | 309,500 ± 7,178 |
| DQ pre-treatment | 0.117 ± 0.014 | 33.933 ± 1.399 | 1.683 ± 0.103Δ | 0.546 ± 0.048 | 280,467 ± 8,272 |
| CQ post-treatment | 0.105 ± 0.028 | 30.125 ± 1.209 | 1.534 ± 0.095 | 0.574 ± 0.040 | 316,857 ± 5,343 |
| DQ post-treatment | 0.102 ± 0.008 | 32.367 ± 0.834 | 1.844 ± 0.098 | 0.631 ± 0.038 | 290,000 ± 7,296 |
| * treatment factor | * treatment factor *** group factor |
** treatment factor * group factor |
** group factor |
Cardiac index (CI) (calculated as the cardiac output divided by body weight), fractional shortening (FS), end-diastolic volume (EDV), end-systolic volume (ESV) and heart rate (HR) were analyzed in CQ and DQ group at two different time points – pre-treatment (week 0 – prior to the administration of Que) and post-treatment (week 6 – at the end of the Que treatment course). Data are presented as mean ± SEM and statistical differences as *p < 0.05, **p < 0.01, ***p < 0.001 treatment/group factor, Δ p < 0.05 vs. CQ pre-treatment (two-way ANOVA paired with Holm-Sidak´s multiple comparisons test).