Study schema. (A) Participants underwent a mapping
procedure, two separate transarterial radioembolization (TARE)
procedures, baseline and post-TARE blood collection and liver tumor
biopsy, and PET/CT before and after TARE. (B) Of 23
participants initially enrolled, 20 were included in the study analyses.
Three participants refused a second biopsy but underwent all other study
events. Four participants died due to hepatic progression after the
first TARE; of these, one underwent a post-TARE biopsy and blood
collection during a paracentesis, while the other three had no follow-up
tissue collection.