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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Bone Miner Res. 2022 Oct 5;37(12):2466–2471. doi: 10.1002/jbmr.4708

Table 3.

Characteristics of MRONJ Patients

Characteristics Total (n=52) IV Bisphosphonates (n = 20) Denosumab (n = 23) IV BP/Denosumab (n = 9)
Age (Years) (Mean ± SD) 62.0 ± 10.4 58.9 ± 11.9 62.4 ± 8.8 67.8 ± 8.9
Female sex, n (%) 39 (75%) 15 (75%) 16 (69.6%) 8 (88.9%)
Race
  White/Non-Hispanic 41 (71.6%) 14 (70.0%) 20 (87.0%) 7 (77.8%)
  Black/Non-Hispanic 8 (15.4%) 5 (25.0%) 2 (8.7%) 1 (11.1%)
  Hispanic 2 (3.8%) 0 1 (4.4%) 1 (11.1%)
  Other 1 (1.9%) 1 (5.0%) 0 0
Comorbidity
  Diabetes 13 (25.0%) 5 (25.0%) 5 (21.7%) 3 (33.3%)
  Hyperlipidemia 26 (50.0%) 7 (35.0%) 14 (60.9%) 5 (55.6%)
  Obesity 14 (26.9%) 7 (35.0%) 4 (17.4%) 3 (33.3%)
Exposure to other medications related to MRONJ
Antiangiogenic meds 4 (7.7%) 1 (5.0%) 1 (4.4%) 2 (22.2%)
mTOR inhibitors 5 (9.6%) 1 (5.0%) 3 (13.0%) 1 (11.1%)
Dental surgery 3 (5.8%) 0 2 (8.7%) 1 (11.1%)