Table 4.
Final Cox regression model for the development of MRONJ
| Parameter | Adjusted Hazard Ratio | 95% CI | P |
|---|---|---|---|
| Age >=65 year | 0.91 | 0.52-1.60 | 0.74 |
| Female sex | 1.22 | 0.64-2.32 | 0.55 |
| Race (black vs. white) | 0.74 | 0.34-1.62 | 0.46 |
| Race (Hispanic/other vs. white) | 0.49 | 0.15-1.59 | 0.23 |
| Prior exposure to mTOR inhibitors | 3.53 | 1.33-9.34 | 0.011 |
| Dental surgery | 8.57 | 2.61-28.11 | 0.0004 |
| Denosumab vs. IV BP | 1.25 | 0.66-2.34 | 0.49 |
| IV BP/Denosumab vs. IV BP | 4.49 | 1.96-10.28 | 0.0004 |