Table 5.
Apparent competitive (with L-P5C) inhibition constantsa
| Compound | Ki (mM) |
|---|---|
| 2 | 1.2 ± 0.1 |
| 10 | 3.5 ± 0.3 |
| 16 | 2.8 ± 0.3 |
| 19 | 0.76 ± 0.06 |
| 17 | 5.7 ± 0.6 |
Measured at pH 7.5 and 26°C with [NADH] fixed at 175 μM.
Apparent competitive (with L-P5C) inhibition constantsa
| Compound | Ki (mM) |
|---|---|
| 2 | 1.2 ± 0.1 |
| 10 | 3.5 ± 0.3 |
| 16 | 2.8 ± 0.3 |
| 19 | 0.76 ± 0.06 |
| 17 | 5.7 ± 0.6 |
Measured at pH 7.5 and 26°C with [NADH] fixed at 175 μM.