Table 4.

Differentially expressed genes (q < 0.1) in all three study groups (human (ED and DBPCFC) and mouse study groups).

GeneID	adj.P.Value_ED	logFC_ED	adj.P.Value_DBPCFC	logFC_DBPCFC	adj.P.Value_MOUSE	logFC_MOUSE
AK2	<0.01	-0.31	0.04	-0.40	0.10	0.99
ARID5A	<0.01	0.98	0.07	0.51	0.10	1.17
ATXN10	0.06	-0.24	0.06	-0.45	0.06	0.77
CCDC50	0.03	-0.37	0.04	-0.60	0.02	-1.07
CERS6	<0.01	-0.39	0.01	-0.49	0.06	1.09
CHD9	0.01	-0.23	0.03	-0.37	0.10	-0.51
CLEC4E	<0.01	1.40	0.02	1.53	0.06	2.25
CPNE2	0.05	0.40	0.04	0.75	0.02	3.35
CRISPLD2	0.06	0.52	0.03	0.99	0.06	2.91
FOS	<0.01	1.51	0.01	0.96	0.06	1.91
FPR1	0.01	0.46	0.02	0.70	0.05	2.52
FPR2	<0.01	0.59	0.01	0.95	0.06	2.29
HDC	<0.01	-2.23	0.04	-1.47	0.01	2.79
HLX	0.02	0.69	0.02	1.24	0.10	1.79
IL1R2	<0.01	1.30	0.03	1.57	0.02	3.40
LMNB1	0.01	0.48	0.04	0.75	0.03	0.86
MCEMP1	<0.01	1.50	0.07	1.36	0.02	1.76
MGA	0.01	-0.34	0.01	-0.63	0.07	-0.43
MGAM	0.02	0.70	0.02	1.16	0.10	1.60
MMP25	0.01	0.70	0.08	0.72	0.09	2.16
MMP9	<0.01	1.93	0.01	2.13	0.07	1.68
MXD1	<0.01	0.50	0.04	0.58	0.02	1.48
OSM	<0.01	1.20	0.01	1.27	0.01	3.02
PLAUR	<0.01	0.73	0.02	0.73	0.06	2.69
PPP1R3B	0.03	0.38	0.04	0.63	0.10	1.41
RAB7A	<0.01	0.65	0.05	0.75	0.10	0.77
S100A8	0.04	0.50	0.08	0.92	0.08	2.06
SAMSN1	<0.01	1.74	0.04	1.27	0.06	1.60
SBNO2	0.01	0.52	0.06	0.61	0.09	1.18

DBPCFC double-blind, placebo-controlled food challenge; ED; emergency department; FC, fold change. Differentially expressed genes are listed in alphabetical order. Downregulated genes are presented in blue and upregulated in red.