Table 2.
GRch38 MHC haplotype (PGF)s with HLA and MIC alleles, gene locations, and number of alleles at each gene locus.
| HLA gene or pseudogene [P] | HLA-allele in GRch38 | Genomic location Chr6, NCBI* | Gene ID | Number of alleles for each genea |
|---|---|---|---|---|
| HLA-F | F*01:03:01:01 | 29,723,434–29,738,532 | 3134 | 59 |
| HLA-V [P] | V*01:01:01:01 | 29,791,906–29,797,807 | 352,962 | 3 |
| HLA-P [P] | P*02:01:01:02 | 29,800,044–29,803,079 | 352,963 | 5 |
| HLA-G | G*01:01:01:05 | 29,826,474–29,831,021 | 3135 | 110 |
| HLA-H [P] | H*02:04 | 29,887,573–29,891,079 | 3136 | 67 |
| HLA-T [P] | T*03:01 | 29,896,443–29,898,947 | 352,964 | 8 |
| HLA-K [P] | K*01:01:01:01 | 29,926,659–29,929,825 | 3138 | 6 |
| HLA-U [P] | U*01:04 | 29,933,764–29,934,880 | 352,965 | 5 |
| HLA-A | A*03:01:01:01 | 29,942,532–29,945,870 | 3105 | 7644 |
| HLA-W [P] | W*01:01:01:05 | 29,955,834–29,959,058 | 352,966 | 11 |
| HLA-J [P] | J*01:01:01:04 | 30,005,971–30,009,956 | 3137 | 33 |
| HLA-L [P] | L*01:01:01:03 | 30,259,562–30,266,951 | 3139 | 5 |
| HLA-N [P] | N*01:01:01:01 | 30,351,074–30,352,038 | 267,014 | 5 |
| HLA-E | E*01:03:02:01 | 30,489,509–30,494,194 | 3133 | 342 |
| HLA-C | C*07:02:01:03 | 31,268,749–31,272,092, comp | 3107 | 7609 |
| HLA-B | B*07:02:01:01 | 31,353,875–31,357,179, comp | 3106 | 9097 |
| HLA-S [P] | S*01:01:01:02 | 31,381,569–31,382,487 | 267,015 | 7 |
| MICA | MICA*008:04 | 31,400,711–31,415,315 | 100,507,436 | 529 |
| MICB | MICB*004:01:01 | 31,494,918–31,511,124 | 4277 | 237 |
| HLA-DRA | DRA*01:02:03 | 32,439,887–32,445,046 | 3122 | 43 |
| HLA-DRB5 | DRB5*01:01:01:01 | 32,517,353–32,530,287, comp | 3127 | 187 |
| HLA-DRB1 | DRB1*15:01:01:01 | 32,578,775–32,589,848, comp | 3123 | 3389 |
| HLA-DQA1 | DQA1*01:02:01:01 | 32,637,406–32,655,272 | 3117 | 508 |
| HLA-DQB1 | DQB1*06:02:01:01 | 32,659,467–32,666,657, comp | 3119 | 2330 |
| HLA-DQA2 | DQA2*01:01:01:03 | 32,741,391–32,747,198 | 3118 | 40 |
| HLA-DQB2 | DQB2*01:02:01 | 32,756,098–32,763,532, comp | 3120 | 18 |
| HLA-DOB | DOB*01:01:01 | 32,812,763–32,817,002, comp | 3112 | 60 |
| HLA-DMB | DMB*01:03:01 | 32,934,636–32,941,028, comp | 3109 | 71 |
| HLA-DMA | DMA*01:01:01 | 32,948,618–32,953,097, comp | 3108 | 58 |
| HLA-DOA | DOA*01:01:02 | 33,004,182–33,009,591, comp | 3111 | 92 |
| HLA-DPA1 | DPA1*01:03:01:02 | 33,064,569–33,080,748 | 3113 | 491 |
| HLA-DPB1 | DPB1*04:01:01:01 | 33,075,990–33,089,696 | 3115 | 2221 |
| HLA-DPA2 | DPA2*01:01:01:01 | 33,091,482–33,093,314, comp | 646,702 | 5 |
| HLA-DPB2 | DPB2*03:01:01:01 | 33,112,516–33,129,113 | 3116 | 6 |
ahttps://www.ebi.ac.uk/ipd/imgt/hla/about/statistics/ 17 October 2022.
*Assembly: GRch38p13 version, NC_000006.12 (https://www.ncbi.nlm.nih.gov/grc/human/regions/MHC?asm=GRCh38.p13).