Table 5.
Six most common HLA haplotype frequencies in six world populations.
| Population and HLA haplotypes (some with CEH/AH designations) | Freq (%) |
|---|---|
| Japanese, 768 families, 3072 haplotypes (Shiina et al., unpublished data) | |
| A*2402-C*1202-B*5201-DRB1*1502-DQA1*0103-DQB1*0601-DPA1*0201-DPB1*0901 | 7.3 |
| A*2402-C*0702-B*0702-DRB1*0101-DQA1*0101-DQB1*0501-DPA1*0103-DPB1*0402 | 3.2 |
| A*3303-C*1403-B*4403-DRB1*1302-DQA1*0102-DQB1*0604-DPA1*0103-DPB1*0401 | 3.1 |
| A*2402-C*0102-B*5401-DRB1*0405-DQA1*0303-DQB1*0401-DPA1*0202-DPB1*0501 | 2.0 |
| A*1101-C*0401-B*1501-DRB1*0406-DQA1*0301-DQB1*0302-DPA1*0103-DPB1*0201 | 1.2 |
| A*0207-C*0102-B*4601-DRB1*0803-DQA1*0103-DQB1*0601-DPA1*0202-DPB1*0202 | 0.9 |
| Chinese, 8608 segregated haplotypes (Li et al.95) | |
| A*3001-C*0602-B*1302-DRB1*0701-DQB1*0202 | 5.0 |
| A*0207-C*0102-B*4601-DRB1*0901-DQB1*0303 | 3.2 |
| A*3303-C*0302-B*5801-DRB1*0301-DQB1*0201 | 2.8 |
| A*3303-C*0302-B*5801-DRB1*1302-DQB1*0609 | 1.5 |
| A*1101-C*0801-B*1502-DRB1*1202-DQB1*0301 | 1.3 |
| A*0207-C*0102-B*4601-DRB1*0803-DQB1*0601 | 0.9 |
| Saudi, 3,588 LD inferred haplotypes (Jawdat et al.96) | |
| A*0201-C*1502-B*5101-DRB1*0402-DQB1*0302-DPB1*0401 | 1.0 |
| A*0201-C*0702-B*0702-DRB1*1501-DQB1*0602-DPB1*0401 | 0.9 |
| A*0201-C*0602-B*5001-DRB1*0701-DQB1*0201-DPB1*0401 | 0.8 |
| A*2301-C*0602-B*5001-DRB1*0701-DQB1*0201-DPB1*0301 | 0.6 |
| A*2402-C*0702-B*0801-DRB1*0301-DQB1*0201-DPB1*0401 | 0.6 |
| A*0101-C*1701-B*4101-DRB1*0701-DQB1*0303-DPB1*0402 | 0.6 |
| British Caucasian, 11,088 PHASE imputed haplotypes (Neville et al.97) | |
| A*0101-C*0701-B*0801-DRB1*0301-DQA1*0501-DQB1*0201 (AH8.1) | 7.5 |
| A*0301-C*0702-B*0702-DRB1*1501-DQA1*0102-DQB1*0602 (AH7.1) | 3.0 |
| A*0201-C*0501-B*4402-DRB1*0401-DQA1*0301-DQB1*0301 (AH44.1) | 2.6 |
| A*0201-C*0702-B*0702-DRB1*1501-DQA1*0102-DQB1*0602 (AH7.x) | 1.8 |
| A*2902-C*1601-B*4403-DRB1*0701-DQA1*0201-DQB1*0202 (AH44.2) | 1.8 |
| A*0101-C*0602-B*5701-DRB1*0701-DQA1*0201-DQB1*0303 (AH57.x) | 1.4 |
| European American, 12768 statistically inferred haplotypes (Maiers et al.98) | |
| A*0101-C*0701-B*0801-DRB1*0301-DQB1*0201 (AH8.1) | 7.4 |
| A*0301-C*0702-B*0702-DRB1*1501-DQB1*0602 (AH7.1) | 3.5 |
| A*0201-C*0501-B*4402-DRB1*0401-DQB1*0301 (AH44.1) | 2.4 |
| A*0201-C*0702-B*0702-DRB1*1501-DQB1*0602 (AH7.x) | 2.3 |
| A*2902-C*1601-B*4403-DRB1*0701-DQB1*0201 g (AH44.2) | 1.8 |
| A*0101-C*0602-B*5701-DRB1*0701-DQB1*0303 (AH57.x) | 1.3 |
| African American, 894 statistically inferred haplotypes (Maiers et al.98) | |
| A*3001-C*1701-B*4201-DRB1*0302-DQB1*0402 (AH42.1) | 1.5 |
| A*0101-C*0701-B*0801-DRB1*0301-DQB1*0201 (AH8.1) | 1.4 |
| A*0301-C*0702-B*0702-DRB1*1501-DQB1*0602 (AH7.1) | 0.9 |
| A*3303-C*0401-B*5301-DRB1*0804-DQB1*0301 | 0.8 |
| A*6802-C*0304-B*1510-DRB1*0301-DQB1*0201 | 0.7 |
| A*6801-C*0602-B* 5802-DRB1*1201-DQB1*0501 (AH58.x) | 0.7 |
The AH nomenclature is taken from Dorak et al.47. The ‘x’ after the AH B allele is an unknown sequential number that needs to be updated.