Fig. 4. Certain REE-matching edits could undergo organized loss in embryos with uniparental disomy and those from elder mothers.

a Count of REE-matching edits that were completely lost in the abnormal uniparental disomy embryos (AG for androgenetic embryos and PG for parthenogenetic embryos) and embryos from elder mothers. See also Supplementary Figs. 23–25 for the sequence coverage of these edits in the pathological embryos/embryos from elder mothers, and Supplementary Figs. 26–28 for their editing levels in normal samples. b Biological processes enriched by four or more genes targeted by AG-lost REE-matching edits. Only those with Benjamini–Hochberg-adjusted (BH-adjusted) p values less than 0.1 were shown.