FIGURE 2.

LPS-induced TCR-γδ ligand expression is dependent on TBK1. Monocytes were untreated or activated with LPS in the absence or presence of the TBK1 inhibitor GSK8612 (10 μM), the TRAF6 inhibitor 6877002 (10 μM), or the TRIF inhibitor resatorvid (10 μM) for 48 h and then stained with sTCR-γδ tetramer-PE (10 μg/ml). (A) Representative histograms with number inserts indicating mean fluorescence intensity of entire histogram. (B) Graphs summarize findings from all experiments. *p < 0.05. ns, not significant.